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EM1404

規(guī)格：	價(jià)格：
50μL	￥1280.00
100μL	￥1980.00

下載說明 ①

Product name:	P63-α (3F11) Mouse mAb
Reactivity:	Human, Rat, Mouse
Source:	Mouse
Dilutions:	WB 1:1,000-2,000?? IHC:1;100-1:200
Immunogen:	Synthetic Peptide
Storage:	PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
Clonality:	Monoclonal
Isotype:	IgG1
Concentration:	1mg/mL
Observed Band:	50-80kDa
GeneID:	8626
Human Swiss-Prot No:	Q9H3D4
Cellular localization:	Nucleus
Background:	p63 can induce p53-responsive genes and apoptosis, mutation of p63 rarely results in tumors . Research investigators frequently observe amplification of the p63 gene in squamous cell carcinomas of the lung, head and neck . The p63 gene contains an alternative transcription initiation site that yields a 40 kDa δNp63 lacking the transactivation domain, and alternative splicing at the carboxy-terminus yields the α, β, and γ isoforms .