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EGFR Mouse mAb
一鍵復(fù)制產(chǎn)品信息
EM1134
規(guī)格： 價(jià)格：
50μL ￥1280.00
100μL ￥1980.00

Overview

Product name: EGFR Mouse mAb
Reactivity: Human
Alternative Names: Epidermal Growth Factor Receptor ;ErbB-1; ErbB1; ER1; ERB-B1; MENA; HER1; Erythroblastic Leukemia Viral(v-Erb-B)oncogene Homolog,Avian; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
Source: Mouse
Dilutions: WB 1:1,000-3,000 IP 1:200 IF 1:100-200
Immunogen: Synthetic Peptide
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed Band: 170kDa
GeneID: 1956
Human Swiss-Prot No: P00533
Background: The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades.
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