| Product name: |
AMACR/P504S Mouse mAb |
| Reactivity: |
Human, Rat, Mouse |
| Alternative Names: |
Alpha-Methylacyl Coenzyme A Racemase ;RACE; 2-methylacyl-CoA racemase |
| Source: |
Mouse |
| Dilutions: |
WB 1:1,000 IHC 1:200 |
| Immunogen: |
Synthetic Peptide |
| Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles. |
| Clonality: |
Monoclonal |
| Isotype: |
IgG1 |
| Concentration: |
1mg/mL |
| Observed Band: |
42kDa |
| GeneID: |
23600 |
| Human Swiss-Prot No: |
Q9UHK6 |
| Cellular localization: |
Peroxisome. Mitochondrion |
| Background: |
AMACR has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of AMACR protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia. |
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