PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1mg/mL
Observed Band:
34,39kDa
GeneID:
5606
Human Swiss-Prot No:
P46734
Cellular localization:
Cytosol,Nucleus
Background:
Three alternatively spliced transcript variants of MEK3 encoding distinct isoforms have been reported. Isoform B utilizes a different start codon compared to isoform C resulting in the production of a N-terminal segment of isoform B which is shorter and distinct from isoform C . MEK3b is the predominant form of MEK3 and strongly activates p38 MAP kinase .