PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1mg/mL
Observed Band:
15-17kDa
GeneID:
8290
Human Swiss-Prot No:
P68431
Cellular localization:
Nuclear
Background:
Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.